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Valget af kraftigt virkende medicin i smertebehandling er en opvejning mellem bivirkninger og virkning samt hvor stærke smerterne er.Der er ingen bivirkninger ved behandlingen med paracetamol, hvis male holder sig til less than hearth gram i døgnet. Canine kan nogle mennesker udvikle hovedpine ved længere tids brug.Hvis TCA har været forsøgt i

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